Cue Biopharma (NASDAQ:CUE – Get Free Report) and MannKind (NASDAQ:MNKD – Get Free Report) are both small-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their dividends, analyst recommendations, institutional ownership, risk, profitability, earnings and valuation.
Institutional and Insider Ownership
35.0% of Cue Biopharma shares are held by institutional investors. Comparatively, 49.5% of MannKind shares are held by institutional investors. 14.6% of Cue Biopharma shares are held by company insiders. Comparatively, 2.6% of MannKind shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.
Earnings & Valuation
This table compares Cue Biopharma and MannKind”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Cue Biopharma | $37.66 million | 5.99 | -$26.60 million | ($27.02) | -1.15 |
| MannKind | $348.97 million | 2.98 | $5.86 million | ($0.13) | -24.88 |
MannKind has higher revenue and earnings than Cue Biopharma. MannKind is trading at a lower price-to-earnings ratio than Cue Biopharma, indicating that it is currently the more affordable of the two stocks.
Risk and Volatility
Cue Biopharma has a beta of 2.45, indicating that its stock price is 145% more volatile than the S&P 500. Comparatively, MannKind has a beta of 1.1, indicating that its stock price is 10% more volatile than the S&P 500.
Profitability
This table compares Cue Biopharma and MannKind’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Cue Biopharma | -435.83% | -620.06% | -291.15% |
| MannKind | -11.08% | -11.21% | -6.31% |
Analyst Ratings
This is a breakdown of recent recommendations for Cue Biopharma and MannKind, as reported by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Cue Biopharma | 1 | 1 | 0 | 1 | 2.33 |
| MannKind | 2 | 1 | 7 | 0 | 2.50 |
Cue Biopharma currently has a consensus price target of $83.00, suggesting a potential upside of 167.27%. MannKind has a consensus price target of $8.34, suggesting a potential upside of 157.92%. Given Cue Biopharma’s higher possible upside, equities research analysts plainly believe Cue Biopharma is more favorable than MannKind.
Summary
MannKind beats Cue Biopharma on 9 of the 15 factors compared between the two stocks.
About Cue Biopharma
Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops a novel class of injectable therapeutics to selectively engage and modulate targeted, disease relevant T cells directly within the patient's body. Its lead drug product candidate is CUE-101 for the treatment of human papilloma virus (HPV16+)-driven recurrent/metastatic head and neck cancer. The company is also developing CUE-102 targets Wilms' Tumor 1 protein in various cancers; CUE-103, a CUE-100 series drug product candidate; and Neo-STAT and RDI-STAT programs outside of oncology, including CUE-200, CUE-300, and CUE-400 series. It has collaboration agreements with LG Chem, Ltd. for the development of Immuno-STATs focused in the field of oncology; strategic collaboration and option agreement with Ono Pharmaceutical Co., Ltd. to advance CUE-401 for the treatment of autoimmune and inflammatory diseases; and license agreement with Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Boston, Massachusetts.
About MannKind
MannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of inhaled therapeutic products for endocrine and orphan lung diseases in the United States. It offers Afrezza, an inhaled insulin used to improve glycemic control in adults with diabetes, and the V-Go wearable insulin delivery device, which provides continuous subcutaneous infusion of insulin in adults. The company's product pipeline also includes Tyvaso DPI (Treprostinil), an inhalation powder for the treatment of pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease; MNKD-101, a nebulized formulation of clofazimine, for the treatment of severe chronic and recurrent pulmonary infections, including nontuberculous mycobacterial lung disease; MNKD-201, a dry-powder formulation of nintedanib, for the treatment of idiopathic pulmonary fibrosis (IPF). In addition, it has collaboration and license agreement with United Therapeutics Corporation for development, regulatory, and commercial activities of Tyvaso DPI; co-promotion agreement with Vertice Pharma to promote Thyquidity; and collaboration agreement with Thirona to evaluate the therapeutic for the treatment of pulmonary fibrosis. Further, the company has supply and distribution agreement with Biomm S.A. for the commercialization of Afrezza in Brazil; and license and distribution agreement with Cipla Ltd. for the marketing and distribution of Afrezza in India. MannKind Corporation was incorporated in 1991 and is headquartered in Danbury, Connecticut.
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