Critical Review: BioCryst Pharmaceuticals (BCRX) vs. INmune Bio (INMB)

BioCryst Pharmaceuticals (NASDAQ:BCRX) and INmune Bio (NASDAQ:INMB) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their risk, institutional ownership, profitability, dividends, valuation, analyst recommendations and earnings.


This table compares BioCryst Pharmaceuticals and INmune Bio’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals -490.25% -175.83% -66.71%
INmune Bio N/A N/A N/A

Institutional & Insider Ownership

91.9% of BioCryst Pharmaceuticals shares are held by institutional investors. 4.5% of BioCryst Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Analyst Recommendations

This is a breakdown of recent ratings and price targets for BioCryst Pharmaceuticals and INmune Bio, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals 0 3 6 0 2.67
INmune Bio 0 0 1 0 3.00

BioCryst Pharmaceuticals presently has a consensus price target of $12.50, suggesting a potential upside of 36.61%. INmune Bio has a consensus price target of $13.00, suggesting a potential upside of 66.45%. Given INmune Bio’s stronger consensus rating and higher possible upside, analysts plainly believe INmune Bio is more favorable than BioCryst Pharmaceuticals.

Earnings and Valuation

This table compares BioCryst Pharmaceuticals and INmune Bio’s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
BioCryst Pharmaceuticals $20.65 million 48.82 -$101.25 million ($0.98) -9.34
INmune Bio N/A N/A N/A N/A N/A

INmune Bio has lower revenue, but higher earnings than BioCryst Pharmaceuticals.


INmune Bio beats BioCryst Pharmaceuticals on 5 of the 9 factors compared between the two stocks.

BioCryst Pharmaceuticals Company Profile

BioCryst Pharmaceuticals, Inc., a biotechnology company, designs, optimizes, and develops small molecule drugs that block key enzymes involved in the pathogenesis of diseases. The company markets peramivir, an intravenous neuraminidase inhibitor, which is approved for uncomplicated seasonal and acute influenza in the United States and Canada under the name RAPIVAB, in Japan and Taiwan as RAPIACTA, and in Korea as PERAMIFLU; and Mundesine, an oral purine nucleoside phosphorylase inhibitor to treat cancer in Japan. It also develops BCX7353 and second generation kallikrein inhibitors, which are oral serine protease inhibitors targeting plasma kallikrein for hereditary angioedema; BCX9250 and BCX9499, which are activin receptor-like kinase-2 inhibitors for fibrodysplasia ossificans progressive; and Galidesivir, a RNA dependent-RNA polymerase inhibitor to treat RNA viruses. The company has collaborations and in-license relationships with U.S. Department of Health and Human Services; National Institute of Allergy and Infectious Diseases; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; and The University of Alabama at Birmingham. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

INmune Bio Company Profile

INmune Bio Inc., a clinical-stage immunotherapy company, focuses on engineering and harnessing the innate immune system to treat the patient's cancer. The company intends to develop and commercialize product candidates to treat diseases comprising hematologic malignancies and solid tumors. Its development programs include INKmune, which focuses on treating women with relapse refractory ovarian carcinoma; and INB03 that treats patients with advanced cancers with elevated biomarkers of inflammation, including elevated levels of myeloid derived suppressor cells in their blood. The company was founded in 2015 and is based in La Jolla, California.

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